01/10/2023

بندر ذياب العنزي

بندر ذياب العنزي
دكتوراه
الطب والخدمات الصحية
University of Liverpool
مجال التميز بحثي دراسي
   
البحوث المنشورة
البحث (1):
عنوان البحث: Global Development on Causes, Epidemiology, Aetiology, and Risk Factors of Prostate Cancer: An Advanced Study
رابط إلى البحث: https://stm.bookpi.org/HMMS-V17/article/view/2615
تاريخ النشر: 22/07/2021
موجز عن البحث: As the second most recurring cancer in men globally, prostate cancer is a major concern to men’s health. It is estimated that approximately 1.3 million new cases are diagnosed every year, those cases are leading to the casualties of nearly 360,000 men during 2018, which represents about 3.8% of all male cancer related deaths. Increasing of age among men can be correlated with global prostate cancer incidence and mortality, with the average age of diagnosis is 66 years old. Prostate cancer is usually asymptomatic or with minimal symptoms in the early stages of the disease, during this period there is minimal to no need of treatment. At early stage, the symptoms of prostate cancer are similar to those observed in prostatic hypertrophy. But in more advanced stages of prostate cancer, more painful symptoms may appear. Elevated levels of Prostate Specific Antigen (PSA) are the main marker used to detect prostate cancer. The disease can be confirmed with a biopsy of the prostate gland. In this work, we try to review the prostate cancer’s causes, epidemiology, aetiology, and risk factors globally, as we think that it is a pivotal way to keep update our understanding on this increasingly important health threat to men.
 
البحث (2):
عنوان البحث: Peroxisome Proliferator-Activated Receptor Gamma (Pparγ) and Prostate Cancer
رابط إلى البحث: https://lupinepublishers.com/cancer-journal/pdf/OAJOM.MS.ID.000206.pdf
تاريخ النشر: 06/12/2021
موجز عن البحث: The fatty acid receptor peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor, which includes two isoforms named PPARγ1 and PPARγ2 respectively. In human body, PPARү involves in metabolic disorder, neurodegenerative disease and inflammation. Recent advance in PPARү study has led to the discoveries of several genes that are regulated by PPARγ in prostate cancer cells. Evidence showed that PPARү plays important roles in development and in malignant progression of prostate cancer. In this mini-review, we described the PPARγ structure and summarized their involvement in different diseases. Our focus is on the roles of PPARγ isoforms in prostate cancer.

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