Saudi Arabia occupies the majority of the
Arabian Peninsula and the genetic structure of its population have been
influenced by the African and Asian surrounding populations. Only four
studies have described the genetic diversity of forensic STRs in the Saudi
population with maximum of 15 STR loci, three of the studies had
representatives not residing Saudi Arabia. In addition, the high percentage
of consanguinity (56%) is a major factor in shaping the genetic structure of
the Saudi population and thus increases the importance of studying the
genetic diversity of this population to evaluate to what extent new STR
markers can be utilised for crime scene and kinship cases.
Here, the data of 21 autosomal STRs
generated by GlobalFiler® PCR amplification kit is presented. Most of the 21
STRs (18/21) show ≥0.9 PoD; SE33 is the most informative locus with 0.993
PoD, and TPOX is the least informative locus with 0.84 PoD. Allele ranges
varied from 6 alleles in TH01 to 44 alleles in SE33.
This study has shown that the 21
STR loci of the GlobalFiler™ PCR Amplification Kit, as expected, provided a
much higher discrimination power in the population of Saudi Arabia compared
to the currently used STR kit. Three of the additional STR loci (SE33,
D12S391, and D1S1656) in this kit are more informative than any locus in the
AmpFlSTR® Identifiler® PCR amplification kit. Therefore, adapting this kit in
the forensic genetics laboratories of Saudi Arabia as a standard STR kit
would be very beneficial.