مجال التميز |
تميز دراسي وبحثي |
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البحوث المنشورة |
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البحث (1): |
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عنوان البحث: |
Vitamin D Intake, Calcium Intake And Physical Activity Among Children With Wrist And Ankle Injuries And The Association With Fracture Risk |
رابط إلى البحث: |
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تاريخ النشر: |
06/02/2019 |
موجز عن البحث: |
Background: Several studies have revealed a substantial increase in the incidence of fractures in children in the past few decades. Aim: To assess the strength of the association between suggested risk factors and fracture prevalence in children. Method: A cross sectional observational study. Children aged 6–15 years and their guardians presenting to the Emergency Department of a single tertiary paediatric hospital were recruited. Self-reported data on vitamin D intake, calcium intake and physical activity were collected. All participants had a radiograph of their injured limb reported by a consultant radiologist, on the basis of which they were classified into fracture or no fracture groups. Statistical analysis included descriptive statistics and binary logistic regression. Results: Of the 130 patients recruited, 53 (41%) had sustained a fracture. The overwhelming majority of children (98%) did not consume the recommended daily dietary amount of vitamin D (400 IU/day). Low calcium intake and low levels of physical activity were also ascertained. However, there were no significant differences between fracture and no fracture groups for vitamin D intake, calcium intake or physical activity. Both site of injury (wrist) and sex (male) were associated with increased fracture risk (p = 0.001 and p = 0.05, respectively). Logistic regression showed a statistically significant relationship between calcium intake and fracture risk (every additional unit of calcium consumption (mg/day) decreased the likelihood of fracture by 0.002, 95% confidence interval, 0.001–0.003). Conclusions: Low dietary intake of calcium and vitamin D and low levels of physical activity were evident. Fracture risk was significantly associated with reduced calcium intake but showed no association with vitamin D intake or physical activity. |
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المؤتمرات العلمية: |
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المؤتمر (1): |
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عنوان المؤتمر: |
The 8th International Conference On Children’s Bone Health (ICCBH) |
تاريخ الإنعقاد: |
10-13 June 2017 |
مكان الإنعقاد: |
Würzburg, Germany |
طبيعة المشاركة: |
Poster presentation |
عنوان المشاركة: |
Impact Of Age, Sex, Location Of Injury, Physical Activity, Vitamin D And Calcium Intake On The Injury Outcome Of Wrist And Ankle In Children |
ملخص المشاركة: |
Objectives: The aim of this study was to assess the impact of age, sex, location of injury, physical activity, dietary intake of calcium and vitamin D on injury outcome in otherwise healthy children. Materials: This study was a cross-sectional prospective study. Children aged 6 to 15 years who presented to the Emergency Department of a single tertiary paediatric referral hospital were recruited. Children were included it they were known not to have underlying disease or long-term medication. Children were not eligible if they had been involved in high-energy trauma as we hypothesised that fracture is more likely to happen regardless of other factors. Patients’ age, sex and injury location were retrieved from their emergency notes. Physical activity were assessed using validated recall questionnaire. Vitamin D and calcium intake were assessed using validated food frequency questionnaire. All participants had a radiograph of their injured limb reported by a consultant radiologist. The patients were classified into two outcome groups (fracture or no facture) based on the imaging findings. Data analysis include descriptive and inferential statistic. Logistic regression was performed to assess the impact of a number of factors on the injury outcome. Results: 130 patients were recruited and of these, 53 (40%) patients sustained a fracture. 119 (91%) and 127 (98%) children did not consume the recommended daily dietary amount of calcium and vitamin D, respectively. Patients’ age, physical activity, vitamin D and calcium intake were not significantly associated with fractures. Sex was found to have a significant effect on injury outcome with males being at higher risk of fracture. Injury to the wrist was significantly associated with an increased risk of fracture. The logistic regression showed that some factors were significant predictors of the injury outcome when controlling for other factors in the model. Conclusion: Children’s lifestyle in this study was poor in terms of dietary intake of vitamin D and calcium as well as their engagement in physical activities. We failed to show any association between these modifiable factors and injury outcome, probably because of the high prevalence amongst the population of low dietary vitamin D and calcium. |
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المؤتمر (2): |
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عنوان المؤتمر: |
Bone Research Society Annual Meeting 2018 |
تاريخ الإنعقاد: |
27-29 June 2018 |
مكان الإنعقاد: |
Winchester, UK |
طبيعة المشاركة: |
Poster presentation |
عنوان المشاركة: |
Correlation Between Serum 25 Hydroxyvitamin D, Parathyroid Hormone (PTH), And High-Resolution Peripheral Quantitative Computed Tomography (HR-Pqct) Parameters Of The Distal Tibia |
ملخص المشاركة: |
Objectives: The aim of this study was to determine the strength of association between serum 25 hydroxyvitamin D, PTH and HR-pQCT parameters of the distal tibia in a young Middle Eastern/North African (MENA) population living in the United Kingdom (UK). Methods: Forty apparently healthy young people who emigrated from the MENA countries to the UK (20 males, 20 females) were recruited. Serum 25 hydroxyvitamin D and PTH levels were determined between November 2017 and March 2018. All blood samples were collected in the morning following an overnight fast. The non-dominant distal tibia of all participants was scanned in order to assess bone microstructure using an XtremeCT HR-pQCT scanner (Scanco Medical). Results: The age of the participants ranged from 18 to 38 years (median=28.1, SD=7). The mean total 25 hydroxyvitamin D was 27.8 nmol/L (SD=19.6, range= 85) while the mean PTH was 71.4 ng/L (SD= 33.5, range=170.50). The correlation results showed that there were weak but significant correlations between PTH and the following HR-pQCT parameters: total density (r=0.364, p=0.024), inner trabecular density (r= 0.340, p=0.037) and trabecular bone volume/tissue volume (r=0.331, p= 0.042). Regression analysis showed that 1) the factors which in combination were most strongly associated with cortical density were calcium intake and sex (adjusted R2= 36.9%), 2) the factors which in combination were most strongly associated with trabecular density were height, PTH, weight, and age (adjusted R2 = 55.9%), and 3) the factors which in combination were most strongly associated with cortical area were weight and sex (adjusted R2= 45.6%). Conclusion: Low levels of vitamin D were evident among this cohort. Despite the low levels of vitamin D, mean PTH was only slightly elevated among this ethnic group who live in the UK. The results of this correlation study indicate that PTH has a greater impact on trabecular bone microstructure than vitamin D. Height, weight, sex, age, calcium intake and PTH were strong predictors of cortical density, trabecular density and cortical area among this cohort. |
المرفقات
- https://uksacb.org/wp-content/uploads/2019/03/BRS-2018-CPD-certificate-H-Alshamrani.pdf
- https://uksacb.org/wp-content/uploads/2019/03/ICCBH-2017-Certificate.pdf
- https://uksacb.org/wp-content/uploads/2019/03/BRS-2018-CPD-certificate-H-Alshamrani.pdf
- https://uksacb.org/wp-content/uploads/2019/03/ICCBH-2017-Certificate.pdf