مجال
التميز
|
تميز دراسي وبحثي
|
|
|
البحوث المنشورة
|
|
البحث (1):
|
|
عنوان البحث:
|
Investigating
the epidemiology of medication errors and error-related adverse drug events
(ADEs) in primary care, ambulatory care and home settings: a systematic
review protocol
|
رابط إلى البحث:
|
Click here
|
تاريخ النشر:
|
31/08/2016
|
موجز عن البحث:
|
Introduction:
There is a need to better understand the epidemiology of medication errors
and error-related adverse events in community care contexts.
Methods
and analysis: We will systematically search the following databases:
Cumulative Index to Nursing and Allied Health Literature (CINAHL), EMBASE,
Eastern Mediterranean Regional Office of the WHO (EMRO), MEDLINE, PsycINFO
and Web of Science. In addition, we will search Google Scholar and contact an
international panel of experts to search for unpublished and in progress
work. The searches will cover the time period January 1990–December 2015 and
will yield data on the incidence or prevalence of and risk factors for
medication errors and error-related adverse drug events in adults living in
community settings (ie, primary care, ambulatory and home). Study quality
will be assessed using the Critical Appraisal Skills Program quality
assessment tool for cohort and case–control studies, and cross-sectional
studies will be assessed using the Joanna Briggs Institute Critical Appraisal
Checklist for Descriptive Studies. Meta-analyses will be undertaken using
random-effects modelling using STATA (V.14) statistical software.
Ethics
and dissemination: This protocol will be registered with PROSPERO, an
international prospective register of systematic reviews, and the systematic
review will be reported in the peer-reviewed literature using Preferred
Reporting Items for Systematic Reviews and Meta-Analyses.
|
|
|
البحث (2):
|
|
عنوان البحث:
|
What is the epidemiology of medication errors,
error-related adverse events and risk factors for errors in adults managed in
community care contexts? A systematic review of the international literature
|
رابط إلى البحث:
|
Click here
|
تاريخ النشر:
|
05/05/2018
|
موجز عن البحث:
|
Objective:
To investigate the epidemiology of medication errors and error-related
adverse events in adults in primary care, ambulatory care and patients’
homes.
Design:
Systematic review.
Data
source: Six international databases were searched for publications between 1
January 2006 and 31 December 2015.
Data
extraction and analysis: Two researchers independently extracted data from
eligible studies and assessed the quality of these using established
instruments. Synthesis of data was informed by an appreciation of the
medicines’ management process and the conceptual framework from the
International Classification for Patient Safety.
Results:
60 studies met the inclusion criteria, of which 53 studies focused on
medication errors, 3 on error-related adverse events and 4 on risk factors
only. The prevalence of prescribing errors was reported in 46 studies:
prevalence estimates ranged widely from 2% to 94%. Inappropriate prescribing
was the most common type of error reported. Only one study reported the
prevalence of monitoring errors, finding that incomplete therapeutic/safety
laboratory-test monitoring occurred in 73% of patients. The incidence of
preventable adverse drug events (ADEs) was estimated as 15/1000 person-years,
the prevalence of drug–drug interaction-related adverse drug reactions as 7%
and the prevalence of preventable ADE as 0.4%. A number of patient,
healthcare professional and medication-related risk factors were identified,
including the number of medications used by the patient, increased patient
age, the number of comorbidities, use of anticoagulants, cases where more
than one physician was involved in patients’ care and care being provided by
family physicians/general practitioners.
Conclusion:
A very wide variation in the medication error and error-related adverse
events rates is reported in the studies, this reflecting heterogeneity in the
populations studied, study designs employed and outcomes evaluated. This
review has identified important limitations and discrepancies in the
methodologies used and gaps in the literature on the epidemiology and
outcomes of medication errors in community settings.
|
|
|
البحث (3):
|
|
عنوان البحث:
|
Investigating the epidemiology of medication errors
in adults in community care settings. A retrospective cohort study in central
Saudi Arabia
|
رابط إلى البحث:
|
Click
here
|
تاريخ النشر:
|
01/02/2019
|
موجز عن البحث:
|
Objectives:
To investigate the period prevalence and risk factors for clinically
important prescription and monitoring errors among adults managed in
community care in Saudi Arabia (SA).
Methods:
This retrospective cohort study used electronic health record (HER) data. A
random sample comprising of 2,000 adults (≥18 years
old) visiting Family Medicine clinics in King Faisal Specialist Hospital and
Research Center (KFSH & RC), Riyadh, SA, was selected. Data collection
took 3 months (October December 2017). Descriptive analyses and logistic regression
modeling were performed using STATA (version 14) statistical software.
Results:
The overall period prevalence of medication errors over 15 months was 8.1%
(95% confidence interval [CI] 6.5-9.7). Risk factors that significantly
predicted overall risk of patients experiencing one or more medication errors
were: age ≥65 years, male gender, Saudi nationality,
and polypharmacy (defined as the concurrent use of ≥5 drugs).
Conclusions:
Clinically important medication errors were commonly observed in relation to
both drug prescription and monitoring.
|
|
|
المؤتمرات العلمية:
|
|
المؤتمر (1):
|
|
عنوان المؤتمر:
|
10th Medication
Safety Conference
|
تاريخ الإنعقاد:
|
27-29
October 2017
|
مكان
الإنعقاد:
|
Abu Dhabi, UAE
|
طبيعة المشاركة:
|
Poster presentation
|
عنوان المشاركة:
|
Investigating
the Epidemiology of Medication Errors and Error-related Adverse Drug Events
in Adults in Primary Care, Ambulatory Care and Home Settings: a Systematic
Review
|
ملخص المشاركة:
|
Purpose:
To explore the epidemiology of medication errors, error-related adverse
events as well as their risk factors in adults in primary care, ambulatory
care and patients’ homes.
Method:
Six biomedical databases were searched between 1st January 2006 and 31
December 2015. A manual review of the bibliographies of all included studies
was also conducted. Two researchers independently extracted relevant data
from eligible studies. The quality of the studies was also assessed
independently by the researchers using the Critical Appraisal Skills Program
quality assessment tool for cohort and case-control studies and the Joanna
Briggs Institute Critical Appraisal Checklist for Descriptive Studies for
cross-sectional studies. Any disagreements were resolved by consensus or
arbitration by a third reviewer if a decision could not be reached.
Descriptive and narrative synthesis was applied to the findings of included
studies.
Results:
A total of 60 studies met the inclusion criteria of which 53 studies focused
on medication errors, three on error-related adverse events and four studies
on risk factors. Based on the medicines’ management process and definitions
of the conceptual framework from the International Classification for Patient
Safety (ICPS), 46 studies reported the prevalence of prescribing errors
between 2-94%. Only one study reported
the prevalence of monitoring error. Incidence was insufficiently evaluated. A
number of patient, healthcare professional and medication-related risk
factors were also identified from included studies.
Conclusion:
In this first community-based systematic review, studies have highlighted
that medication errors occur in adults, with most of the errors occurring at
the prescribing stage. Our study has identified important limitations and
discrepancies in the methodologies used and gaps in the literature in
reporting the incidence of medication errors and investigating errors
occurring at administration and dispensing stages of the medicines’
management process.
|
|
|
المؤتمر (2):
|
|
عنوان المؤتمر:
|
4th Global
Ministerial Summit on Patient Safety
|
تاريخ الإنعقاد:
|
02/03/2019
|
مكان
الإنعقاد:
|
Jeddah, KSA
|
طبيعة المشاركة:
|
Poster presentation
|
عنوان المشاركة:
|
Investigating
the epidemiology of medication errors in adults in community care settings. A
retrospective cohort study in central Saudi Arabia
|
ملخص المشاركة:
|
Introduction:
Medication errors are a major problem in all care settings. There is a need
to investigate the epidemiology of medication errors in community care
settings in Saudi Arabia (SA).
Rationale/Objectives:
To investigate the period prevalence of and risk factors for clinically
important prescribing and monitoring errors among adults managed in community
care in SA.
Methods:
A phased approach was undertaken beginning with feasibility and pilot work;
followed by a retrospective cohort study using electronic health record (EHR)
derived data in Riyadh, SA. A random sample of 2,000 adults (≥18
years old) visiting one Family Medicine in Riyadh, SA, was selected. Data
collection took three months (01 October to 31 December 2017). Descriptive
analyses and logistic regression modelling were performed using STATA
(version 14) statistical software.
Results:
The overall period prevalence of medication errors over 15 months was 8.1%
(95% confidence interval [CI] 6.5-9.7). Risk factors that significantly
predicted overall risk of patients experiencing one or more medication errors
were: i) age ≥65 years, ii) male gender, iii) Saudi
nationality, and iv) the concurrent use of ≥5 drugs
(polypharmacy).
Conclusions:
This is the first study to investigate medication errors in community
settings in
SA.
Clinically important medication errors were commonly observed in relation to
both drug prescribing and monitoring. Future research should replicate this
work in different community contexts in SA and other countries, in order to
investigate in greater depth the error-related adverse events and develop and
evaluate interventions to decrease clinically important errors in medicine
management.
|