مجال التميز |
تميز دراسي و بحثي |
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البحوث المنشورة |
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البحث (1): |
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عنوان البحث: |
Optical Glucose Sensors Based On Hexagonally-Packed 2.5-Dimensional Photonic Concavities Imprinted In Phenylboronic Acid Functionalized Hydrogel Films |
رابط إلى البحث: |
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تاريخ النشر: |
23/11/2017 |
موجز عن البحث: |
Continuous glucose monitoring aims to achieve accurate control of blood glucose concentration to prevent hypo/hyperglycaemia in diabetic patients. Hydrogel-based systems have emerged as a reusable sensing platform to quantify biomarkers in high-risk patients at clinical and point-of-care settings. The capability to integrate hydrogel-based systems with optical transducers will provide quantitative and colorimetric measurements via spectrophotometric analyses of biomarkers. Here, we created an imprinting method to rapidly produce 2.5D photonic concavities in phenylboronic acid functionalized hydrogel films. Our method exploited diffraction properties of hexagonally-packed 2.5D photonic microscale concavities having a lattice spacing of 3.3 μm. Illumination of the 2.5D hexagonally-packed structure with a monochromatic light source in transmission mode allowed reversible and quantitative measurements of variation in the glucose concentration based on first order lattice interspace tracking. Reversible covalent phenylboronic acid coupling with cis-diols of glucose molecules expanded the hydrogel matrix by ∼2% and 34% in the presence of glucose concentrations of 1 mM and 200 mM, respectively. A Donnan osmotic pressure induced volumetric expansion of the hydrogel matrix due to increasing glucose concentrations (1–200 mM), resulted in a nanoscale modulation of the lattice interspace, and shifted the diffraction angle (∼45° to 36°) as well as the interspacing between the 1st order diffraction spots (∼8 to 3 mm). The sensor exhibited a maximum lattice spacing diffraction shift within a response time of 15 min in a reversible manner. The developed 2.5D photonic sensors may have application in medical point-of-care diagnostics, implantable chips, and wearable continuous glucose monitoring devices. |
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البحث (2): |
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عنوان البحث: |
Laser‐Induced Surface Modification Of Contact Lenses |
رابط إلى البحث: |
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تاريخ النشر: |
26/02/2018 |
موجز عن البحث: |
The authors report on the laser‐induced modification of surface properties of contact lenses. Selective areas of the surface of commercial silicon‐hydrogel contact lenses are patterned in array formats using different powers of the CO2 laser. |
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المؤتمرات العلمية: |
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المؤتمر (1): |
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عنوان المؤتمر: |
Nanotech,Biotech And Surtech Middle East 2017 Conference And Exhibition |
تاريخ الإنعقاد: |
04/12/2017 |
مكان الإنعقاد: |
Dubai. UAE |
طبيعة المشاركة: |
Poster presentation |
عنوان المشاركة: |
Optical Glucose Sensors Based On Imprinted Nanopatterns In Hydrogel System |
ملخص المشاركة: |
Hydrogel-based systems have emerged as a reusable sensing platform to quantify biomarkers in high-risk patients at clinical and point-of-care settings. The capability to integrate hydrogel-based systems with optical transducers will provide quantitative and colorimetric measurements via spectrophotometric analyses of biomarkers. |
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المؤتمر (2): |
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عنوان المؤتمر: |
FEAST International Conference On Design, Engineering, Basic & Applied Sciences And Information Technology: Challenges In Globalized Digital Era (DEA-19) |
تاريخ الإنعقاد: |
12/01/2019 |
مكان الإنعقاد: |
London.UK |
طبيعة المشاركة: |
Poster presentation |
عنوان المشاركة: |
Laser-Induced Surface Modification Of Contact Lenses For Measuring Intraocular Pressure For Glaucoma Patients |
ملخص المشاركة: |
The aim of this project is to investigate the feasibility of using channels to measure intraocular pressure change for glaucoma patients. . Selective areas of the surface of commercial silicon-hydrogel contact lenses were patterned in array formats using different powers of the CO2 laser. 1D arrays of different groove densities, ring-shaped channels, were fabricated. Surface profile properties had different the space gap between the fabricated ring-shaped channels, which were controlled by the beam exposure time, beam power, and scan speed. The CO2 laser was used to create channels on the surface of the contact lenses. Via refinement of laser parameters, the surface geometry of polymer contact lens has obtained an excellent level of channels that may led to hydrophilic and intraocular pressure (IOP) measurable characteristics. A novel technique in fabricating contact lenses having excellent quality via the use of a continuous CO2 laser (λ=μm, Power=W and Speed=mm/s) is detailed here. |
المرفقات
- https://uksacb.org/wp-content/uploads/2019/08/NanotechBiotech-and-Surtech-Middle-East-2017-Conference-and-Exhibition.pdf
- https://uksacb.org/wp-content/uploads/2019/08/The_FEAST_conference_London-Yousef_Alqurashi.jpg
- https://uksacb.org/wp-content/uploads/2019/08/NanotechBiotech-and-Surtech-Middle-East-2017-Conference-and-Exhibition.pdf
- https://uksacb.org/wp-content/uploads/2019/08/The_FEAST_conference_London-Yousef_Alqurashi.jpg