مجال التميز | تميز دراسي وبحثي |
البحوث المنشورة |
|
البحث (1): | |
عنوان البحث: | Effect of Religious Fasting in Ramadan on Blood Pressure: Results From LORANS (London Ramadan Study) and a Meta‐Analysis |
رابط إلى البحث: | https://www.ahajournals.org/doi/10.1161/JAHA.120.021560 |
تاريخ النشر: | 08/10/2021 |
موجز عن البحث: | Background
Ramadan fasting is practiced by hundreds of millions every year. This ritual practice changes diet and lifestyle dramatically; thus, the effect of Ramadan fasting on blood pressure must be determined.
Methods and Results LORANS (London Ramadan Study) is an observational study, systematic review, and meta‐analysis. In LORANS, we measured systolic blood pressure (SBP) and diastolic blood pressure (DBP) of 85 participants before and right after Ramadan. In the systematic review, studies were retrieved from PubMed, Embase, and Scopus from inception to March 3, 2020. We meta‐analyzed the effect from these studies and unpublished data from LORANS. We included observational studies that measured SBP and/or DBP before Ramadan and during the last 2 weeks of Ramadan or the first 2 weeks of the month after. Data appraisal and extraction were conducted by at least 2 reviewers in parallel. We pooled SBP and DBP using a random‐effects model. The systematic review is registered with PROSPERO (International Prospective Register of Systematic Reviews; CRD42019159477). In LORANS, 85 participants were recruited; mean age was 45.6±15.9 years, and 52.9% (n=45) of participants were men. SBP and DBP after Ramadan fasting were lower by 7.29 mm Hg (−4.74 to −9.84) and 3.42 mm Hg (−1.73 to −5.09), even after adjustment for potential confounders. We identified 2778 studies of which 33 with 3213 participants were included. SBP and DBP after/before Ramadan were lower by 3.19 mm Hg (−4.43 to −1.96, I2=48%) and 2.26 mm Hg (−3.19 to −1.34, I2=66%), respectively. In subgroup analyses, lower blood pressures were observed in the groups who are healthy or have hypertension or diabetes but not in patients with chronic kidney disease.
Conclusions Our study suggests beneficial effects of Ramadan fasting on blood pressure independent of changes in weight, total body water, and fat mass and supports recommendations for some governmental guidelines that describe Ramadan fasting as a safe religious practice with respect to blood pressure. |
المؤتمرات العلمية |
|
المؤتمر (1): | |
عنوان المؤتمر: | the BIMA National Conference, Birmingham 7th December 2019 |
تاريخ الإنعقاد: | 07/12/2019 |
مكان الإنعقاد: | UK/Birmingham |
طبيعة المشاركة: | Poster |
عنوان المشاركة: | The Impact of Ramadan Fasting on Health |
ملخص المشاركة: | Background
Ramadan fasting is one of the five pillars of Islam. The number of studies conducted to explore the impact of Ramadan fasting on health is relatively low compared to the number of Muslims who perform this religious practice every year. Previous studies reported contradictory results about how Ramadan fasting affects health.
Methods
Five clinics in five different mosques in London were set up to collect data twice from worshippers. We collected data from 85 participants (45 men and 40 women, age 45.39 ± 15.89). The first visit was one week before Ramadan and the second visit was during the second week of Shawaal (the month after Ramadan). Collected data included Blood pressure, blood samples and body composition. Also, we asked participants to fill out a three days’ food diary before and during Ramadan to monitor change in food intake. Moreover, participants answered a questionnaire about different aspects of their lifestyle such as sleep pattern and smoking before and after Ramadan.
Results
We reported a significant reduction in systolic and diastolic blood pressure with mean differences of 7.30 mm Hg (p-value < 0.001) and 3.42 mm Hg (p-value < 0.001) respectively. Likewise, a significant reduction was noticed in weight (mean difference = 1.60 kg, p-value < 0.001), waist circumference (mean difference= 1.83 cm, p-value= 0.004), hip-circumference (mean difference= 3.05 cm, p-value < 0.001), fat percentage (mean difference = 0.92 kg, p-value= 0.002), fat mass (mean difference= 1.19 kg, p-value < 0.001). There was non-significant reduction in fat free mass (mean difference= 0.50 kg, p-value= 0.15). The rest of data are understudy.
Conclusions
Our study showed that Ramadan fasting is significantly associated with a positive reduction in blood pressure and most of anthropometric measures. However, it is still not clear whether these changes are temporary or permanent.
Acknowledgement
This study was partially funded by the Royal Embassy of Saudi Arabia , Cultural Bureau, London |
رامي خليفة راكان آل جعفر
دكتوراه
الطب والخدمات الصحية
Imperial College London